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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTY2D1 All Species: 18.79
Human Site: S299 Identified Species: 34.44
UniProt: Q68D10 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68D10 NP_919261.2 685 75546 S299 S G N S S Q P S L R E G H D K
Chimpanzee Pan troglodytes XP_508321 684 75407 S299 S G N S S Q P S L R E G H D K
Rhesus Macaque Macaca mulatta XP_001082108 684 75599 S299 S G N S S Q P S L R E G H D R
Dog Lupus familis XP_534086 793 86791 L410 S V N C S Q P L L R E G H N R
Cat Felis silvestris
Mouse Mus musculus Q68FG3 682 74799 S298 S G S S T Q P S L R E G H N R
Rat Rattus norvegicus XP_002725626 681 74519 S298 S G S S S Q P S L R E G H S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517926 644 69600 G251 L E R R N K R G D R G K E G R
Chicken Gallus gallus XP_421015 633 66869 D256 K L S R S A A D K H A P P K S
Frog Xenopus laevis Q6NU13 800 83727 S403 S A R S V G E S G S R S G K P
Zebra Danio Brachydanio rerio Q6DGN6 629 69420 D260 N P Q K K H V D R D G K N G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IMP6 581 65683 E223 D P N A E K L E E E R K K R Q
Honey Bee Apis mellifera XP_395689 579 67372 R221 T L G H R R K R K L V V K E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793115 639 72247 K254 T E R S V V K K A N G Q M N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.7 73.6 N.A. 80.5 82.1 N.A. 55.6 47.8 43 42.7 N.A. 28.3 23.2 N.A. 24
Protein Similarity: 100 99.5 98.5 78.8 N.A. 89.9 90.3 N.A. 66.5 58 56.6 58.6 N.A. 44.2 41.6 N.A. 39.8
P-Site Identity: 100 100 93.3 66.6 N.A. 73.3 80 N.A. 6.6 6.6 20 0 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 100 93.3 N.A. 26.6 13.3 20 20 N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 8 8 0 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 16 8 8 0 0 0 24 0 % D
% Glu: 0 16 0 0 8 0 8 8 8 8 47 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 39 8 0 0 8 0 8 8 0 24 47 8 16 0 % G
% His: 0 0 0 8 0 8 0 0 0 8 0 0 47 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 8 8 16 16 8 16 0 0 24 16 16 16 % K
% Leu: 8 16 0 0 0 0 8 8 47 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 39 0 8 0 0 0 0 8 0 0 8 24 0 % N
% Pro: 0 16 0 0 0 0 47 0 0 0 0 8 8 0 8 % P
% Gln: 0 0 8 0 0 47 0 0 0 0 0 8 0 0 8 % Q
% Arg: 0 0 24 16 8 8 8 8 8 54 16 0 0 8 47 % R
% Ser: 54 0 24 54 47 0 0 47 0 8 0 8 0 8 8 % S
% Thr: 16 0 0 0 8 0 0 0 0 0 0 0 0 0 16 % T
% Val: 0 8 0 0 16 8 8 0 0 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _